Author/Authors :
Ohta، نويسنده , , Shinji and Uy، نويسنده , , Mylene M. and Yanai، نويسنده , , Mihoko and Ohta، نويسنده , , Emi and Hirata، نويسنده , , Toshifumi and Ikegami، نويسنده , , Susumu، نويسنده ,
Abstract :
A new 20-membered macrolide designated exiguolide has been isolated from the marine sponge Geodia exigua, and its structure determined by interpretation of spectroscopic data. Exiguolide specifically inhibited fertilization of sea urchin (Hemicentrotus pulcherrimus) gametes but not embryogenesis of the fertilized egg.
