Title of article
Novel route to the synthesis of 4-quinolyl isothiocyanates
Author/Authors
Zhong، نويسنده , , Boyu and Al-Awar، نويسنده , , Rima S. and Shih، نويسنده , , Chuan and Grimes Jr.، نويسنده , , John H. and Vieth، نويسنده , , Michal and Hamdouchi، نويسنده , , Chafiq، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
4
From page
2161
To page
2164
Abstract
4-Quinolyl isothiocyanates were synthesized in a regiospecific fashion from the corresponding 4-chloroquinolines and silver thiocyanate in refluxing toluene. The products were isolated in quantitative yield and high purity (>95%) by simple filtration and concentration. Reactivity and mechanism of the reaction are discussed. The new approach would provide a new mean which had been lacking for the synthesis of functionalized 4-quinolinyl isothiocyanate.
Keywords
Thiocyanate , 4-Quinolyl isothiocyanate , Silver thiocyanate
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1849342
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