Title of article
New, diastereoselective synthesis of 1-alkyl-5-alkylidene-3-methylidenepyrrolidin-2-ones
Author/Authors
Albrecht، نويسنده , , Anna and K?dzia، نويسنده , , Jacek F. Koszuk، نويسنده , , Jacek F. and Warzycha، نويسنده , , Edyta and Janecki، نويسنده , , Tomasz، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
3
From page
2353
To page
2355
Abstract
The diastereoselective synthesis of 1-alkyl-5-alkylidene-3-methylidenepyrrolidin-2-ones was readily accomplished in a two-step reaction sequence consisting of the reaction of 2-diethoxyphosphoryl-4-oxoalkanoates with amines followed by Horner–Wadsworth–Emmons olefination of formaldehyde using the intermediate 1-alkyl-5-alkylidene-3-diethoxyphosphorylpyrrolidin-2-ones.
Keywords
Pyrrolidinones , Horner–Wadsworth–Emmons olefination , ?-Methylidene-?-lactams
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1849426
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