Title of article
Efficient, highly regioselective, and stereospecific conversion of glycidol systems into C2-O-acylated vicinal halohydrins
Author/Authors
Stamatov، نويسنده , , Stephan D. and Stawinski، نويسنده , , Jacek، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
5
From page
2543
To page
2547
Abstract
Glycidyl esters and ethers undergo a regioselective and stereospecific opening of the oxirane ring upon treatment in chloroform in the presence of pyridine with trimethylsilyl halide (TMSX, X = Cl, Br, or I) and a mixture of carboxylic acid (CA)–trifluoroacetic anhydride (TFAA), to produce the corresponding C2-O-acylated vicinal halohydrins in high yields.
Keywords
Glycidol , carboxylic acids , Trimethylsilyl halides , Trifluoroacetic anhydride , Vicinal haloesters
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1849532
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