Title of article :
Solid-phase synthesis of palmitoylated and farnesylated lipopeptides employing the fluoride-labile PTMSEL linker
Author/Authors :
Maria Lumbierres، نويسنده , , Maria A. Palomo، نويسنده , , Jose M. and Kragol، نويسنده , , Goran and Waldmann، نويسنده , , Herbert، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Abstract :
Acid- and base-labile S-palmitoylated and S-farnesylated lipopeptides can be synthesized in high overall yield employing the (2-phenyl-2-trimethylsilyl) ethyl (PTMSEL) linker for anchoring to and release under almost neutral conditions from the solid support.
Keywords :
solid-phase synthesis , Linker groups , Lipopeptides , Ras protein
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
