Author/Authors :
Li، نويسنده , , Lu and Itoh، نويسنده , , Masahiro and Ablake، نويسنده , , Maila and Macr?̀، نويسنده , , Battesimo and Bendtzen، نويسنده , , Klaus and Nicoletti، نويسنده , , Ferdinando، نويسنده ,
Abstract :
We studied the effect of exogenously administered recombinant human interleukin (IL)-6 on the development of experimental autoimmune orchitis (EAO) in C3H/Hej mice. IL-6 significantly reduced histological signs of EAO and appearance of delayed type hypersensitivity against the immunizing testicular germinal cells. The effect was seen even though the cytokine was administered for only 6 consecutive days and 2 weeks after immunization.
