Title of article
A mild and environmentally acceptable synthetic protocol for chemoselective α-bromination of β-keto esters and 1,3-diketones
Author/Authors
Khan، نويسنده , , Abu T. and Goswami، نويسنده , , Papori and Choudhury، نويسنده , , Lokman H.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
4
From page
2751
To page
2754
Abstract
A wide variety of unsubstituted β-keto esters can be brominated chemoselectively to the corresponding α-monobromo-β-keto esters by using a combination of vanadium pentoxide, hydrogen peroxide and ammonium bromide in a biphasic system, dichloromethane–water at 0–5 °C. In addition, α-mono substituted β-keto esters, cyclic β-keto-esters and 1,3-diketones can also be brominated selectively using the same protocol.
Keywords
?-Bromination , ?-keto esters , Hydrogen peroxide , Ammonium bromide , ?-Bromo-?-keto esters , Vanadium pentoxide
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1849676
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