Title of article :
Stereochemistry of 1-hydroxyphosphonate–phosphate rearrangement. Retention of configuration at the phosphorus atom
Author/Authors :
Jankowski، نويسنده , , Stefan and Marczak، نويسنده , , Justyna and Olczak، نويسنده , , Andrzej and G??wka، نويسنده , , Marek L.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Abstract :
1-Hydroxyphosphonate 1 in the presence of triethylamine in acetonitrile solution undergoes irreversible rearrangement to phosphate 2 and reversible retro-phospho-aldol (retro-Abramov) reaction. The X-ray structures for 1 and 2 revealed that the phosphonate–phosphate rearrangement occurs with retention of configuration at the phosphorus atom.
Keywords :
Phosphonate–phosphate rearrangement , Stereochemistry , nucleophilic substitution , Reaction Mechanism , retro-Abramov reaction
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
