Title of article :
Synthesis of the 11-membered ring of the marine alkaloids, madangamines
Author/Authors :
Yoshimura، نويسنده , , Yuta and Inoue، نويسنده , , Junji and Yamazaki، نويسنده , , Naoki and Aoyagi، نويسنده , , Sakae and Kibayashi، نويسنده , , Chihiro، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Abstract :
The first successful attempt at synthesizing the 11-membered ring of madangamine alkaloids is described. The synthesis involves intramolecular N,O-acetalization of a cyclohexanone derivative, cross-coupling reaction with (Z)-vinylstannane, and intramolecular reductive amination for elaboration of the 11-membered macrocycle.
Keywords :
alkaloid , Madangamine , N , Macrocyclization , O-acetalization
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
