Title of article :
New synthesis of cis-3,4-diaryl-1-tosylpyrrolidines
Author/Authors :
Chang، نويسنده , , Meng-Yang and Pai، نويسنده , , Chun-Li and Lin، نويسنده , , Chun-Yu، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Abstract :
Unsymmetrically substituted cis-3,4-diarylpyrrolidines are synthesized in nearly 25% overall yields starting from 4-aryl-1,2,5,6-tetrahydropyridines by iterative reactions using the combination of m-chloroperoxybenzoic acid (MCPBA) and boron trifluoride etherate (BF3·OEt2) followed by Grignard addition, elimination and hydrogenation sequence.
Keywords :
Grignard addition , 4-Diarylpyrrolidines , m-Chloroperoxybenzoic acid , 4-aryl-1 , 2 , 5 , 6-Tetrahydropyridines , 3-Arylpyrrolines , cis-3 , Boron trifluoride etherate
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
