Title of article
New synthesis of cis-3,4-diaryl-1-tosylpyrrolidines
Author/Authors
Chang، نويسنده , , Meng-Yang and Pai، نويسنده , , Chun-Li and Lin، نويسنده , , Chun-Yu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
4
From page
3641
To page
3644
Abstract
Unsymmetrically substituted cis-3,4-diarylpyrrolidines are synthesized in nearly 25% overall yields starting from 4-aryl-1,2,5,6-tetrahydropyridines by iterative reactions using the combination of m-chloroperoxybenzoic acid (MCPBA) and boron trifluoride etherate (BF3·OEt2) followed by Grignard addition, elimination and hydrogenation sequence.
Keywords
Grignard addition , 4-Diarylpyrrolidines , m-Chloroperoxybenzoic acid , 4-aryl-1 , 2 , 5 , 6-Tetrahydropyridines , 3-Arylpyrrolines , cis-3 , Boron trifluoride etherate
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1850401
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