Title of article :
Furanyl spiroketals: thermodynamic control of remote asymmetry
Author/Authors :
Cahill، نويسنده , , Shane and O’Brien، نويسنده , , Matthew، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Abstract :
(E,E)-2-Alkyl-8-furanyl-1,7-dioxa-spiro[5.5]undecanes (1a–i) have been prepared in good yield and with very high diastereoselectivity from lactones (2a–e) and alkynes (3a,b) using lithium acetylide coupling, hydrogenation, desilylation and acid catalysed cyclisation/equilibration.
Keywords :
spiroketals , Remote asymmetry , Furanyl ethers , Anomeric effect
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
