Title of article
Solvent free preparation of amidophosphonates from isocyanides
Author/Authors
Kaïm، نويسنده , , Laurent El and Grimaud، نويسنده , , Laurence and Hadrot، نويسنده , , Simon، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
3
From page
3945
To page
3947
Abstract
New amidophosphonates are prepared via a two-step Mannich/Ugi one-pot procedure from isocyanides. Aminophosphonates are readily prepared from primary amines, dialkyl phosphites and carbonyl compounds under LiClO4 catalysis without any solvent. After completion, addition of an isocyanide, an aldehyde and acetic acid give access to phosphono Ugi-type adducts in good to moderate yields.
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1850579
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