Title of article
Highly efficient chiral PNNP ligand for asymmetric transfer hydrogenation of aromatic ketones in water
Author/Authors
Xing، نويسنده , , Yan and Chen، نويسنده , , Jian-Shan and Dong، نويسنده , , Zhen-rong and Li، نويسنده , , Yan-Yun and Gao، نويسنده , , Jing-Xing، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
3
From page
4501
To page
4503
Abstract
Chiral PNNP ligand II and [IrHCl2(COD)]2 were applied for the first time in the asymmetric transfer hydrogenation of aromatic ketones with HCOONa in water, giving the corresponding optical alcohols in high yield and excellent enantioselectivity (up to 99% ee). Particularly, the reduction of propiophenone proceeded smoothly at a substrate to catalyst molar ratio of 8000, without compromising the ee values obtained.
Keywords
Asymmetric transfer hydrogenation , Aromatic ketone , chiral ligand
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1850872
Link To Document