Title of article :
Selective functionalizations of 2-phenylpyridine: lactones upon organic versus organometallic activations
Author/Authors :
Xu، نويسنده , , Yiming and Aldeco-Pérez، نويسنده , , Eugenia and Rudler، نويسنده , , Henri and Parlier، نويسنده , , Andrée and Alvarez، نويسنده , , Cecilio، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Abstract :
2-Phenylpyridine activated by chromium tricarbonyl reacts with bis(TMS) ketene acetals to give pyridine-substituted bicyclic γ-lactones. On the other hand, its reaction with the same acetals leads, upon activation with methylchloroformate, to dihydropyridines which can be oxidized to highly substituted, lactone-containing piperidines.
Keywords :
Phenylpyridine , Bis(TMS) ketene acetals , nucleophilic additions , ?- and ?-Lactones
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
