Author/Authors :
Bose، نويسنده , , Ajay K. and Ganguly، نويسنده , , Subhendu N. and Manhas، نويسنده , , Maghar S. and Guha، نويسنده , , Atri and Pombo-Villars، نويسنده , , Esteban، نويسنده ,
Abstract :
Microwave-induced organic reaction enhancement (‘MORE’) chemistry technique (open vessel; controlled microwave energy to stay below the boiling point of the reaction mixture) was used for the N-formylation of aliphatic and aromatic amines and amino heterocycles with aq formic acid (80%) on a multiple gram scale in a few minutes.
Keywords :
N-formylation , Aqueous reaction , Open vessel , Microwaves , Scale-up
