Title of article :
Directed regioselectivity of bromination of ketones with NBS: solvent-free conditions versus water
Author/Authors :
Igor Pravst، نويسنده , , Igor and Zupan?i?، نويسنده , , Marko and Stavber، نويسنده , , Stojan، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Abstract :
The reaction conditions employed directed the site of functionalisation of ketones with NBS: under solvent-free conditions α-bromination was the exclusive process, while in water, ring functionalisation occurred in the case of methoxy substituted aromatic ketones.
Keywords :
ketones , Bromination , Neat , NBS , solvent-free , water , regioselectivity
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
