A one-pot selective deprotective acetylation of benzyl ethers and OTBDMS ethers using the BF3·Et2O–NaI–Ac2O reagent system

An efficient selective deprotection followed by acetylation of several benzyl ethers, including 6-OBn ethers of monosaccharides, and -OTBDMS ethers has been developed by using the BF3·Et2O–NaI–Ac2O reagent system. In addition, both benzylidene and isopropylidene groups are deprotected to form the corresponding diacetates.