Author/Authors :
Kureshy، نويسنده , , Rukhsana I. and Singh، نويسنده , , Surendra and Khan، نويسنده , , Noor-ul H. and Abdi، نويسنده , , Sayed H.R. and Agrawal، نويسنده , , Santosh and Mayani، نويسنده , , Vishal J. and Jasra، نويسنده , , Raksh V. Jasra، نويسنده ,
Abstract :
Catalytic asymmetric ring opening of cyclohexene oxide and meso-stilbene oxide with anilines was catalyzed by a Ti-(S)-(−)-BINOL complex to afford β-amino alcohols in high yield (up to 95%) and good enantioselectivities (ee up to 55%) under microwave irradiation. The reaction using a microwave was found to be 10 times faster than traditional oil-bath heating with retention of enantioselectivity.
Keywords :
Aniline , Ti-BINOL complex , microwave irradiation , Ring opening , epoxides
