Title of article
Microwave-assisted asymmetric ring opening of meso-epoxides with aromatic amines catalyzed by a Ti-S-(−)-BINOL complex
Author/Authors
Kureshy، نويسنده , , Rukhsana I. and Singh، نويسنده , , Surendra and Khan، نويسنده , , Noor-ul H. and Abdi، نويسنده , , Sayed H.R. and Agrawal، نويسنده , , Santosh and Mayani، نويسنده , , Vishal J. and Jasra، نويسنده , , Raksh V. Jasra، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
3
From page
5277
To page
5279
Abstract
Catalytic asymmetric ring opening of cyclohexene oxide and meso-stilbene oxide with anilines was catalyzed by a Ti-(S)-(−)-BINOL complex to afford β-amino alcohols in high yield (up to 95%) and good enantioselectivities (ee up to 55%) under microwave irradiation. The reaction using a microwave was found to be 10 times faster than traditional oil-bath heating with retention of enantioselectivity.
Keywords
Aniline , Ti-BINOL complex , microwave irradiation , Ring opening , epoxides
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1851436
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