Title of article
A new asymmetric synthesis of (+)-12b-epidevinylantirhine
Author/Authors
Allin، نويسنده , , Steven M. and Khera، نويسنده , , Jagjit S. and Witherington، نويسنده , , Jason and Elsegood، نويسنده , , Mark R.J.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
3
From page
5737
To page
5739
Abstract
We report a new asymmetric synthesis of the indole alkaloid derivative (+)-12b-epidevinylantirhine through stereoselective cyclization of a tethered indole nucleus onto an N-acyliminium ion intermediate, generated from a readily available non-racemic bicyclic lactam building block, and subsequent template modification through a highly diastereoselective conjugate addition protocol. In addition, we present the first X-ray crystal structure of this indole target.
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1851880
Link To Document