Title of article :
Proline catalyzed two-component, three-component and self-asymmetric Mannich reactions promoted by ultrasonic conditions
Author/Authors :
Kantam، نويسنده , , M. Lakshmi and Rajasekhar، نويسنده , , Ch.V. and Gopikrishna، نويسنده , , G. and Rajender Reddy، نويسنده , , K. and Choudary، نويسنده , , B.M.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Abstract :
The proline catalyzed two-component and three-component asymmetric Mannich reaction with hydroxyacetone and self-Mannich reaction with propanal were performed successfully under ultrasonic conditions in 1 h to afford Mannich products in 90–98% isolated yields and 81–99% ees with excellent diastereoselectivities.
Keywords :
Organo catalysis , Mannich reaction , asymmetric synthesis , proline , Ultrasonic conditions
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
