Title of article
First lipase catalysed resolution of epoxy enol esters
Author/Authors
JH Gravil، نويسنده , , Sébastien and Veschambre، نويسنده , , Henri and Chênevert، نويسنده , , Robert G. Bolte، نويسنده , , Jean، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
5
From page
6153
To page
6157
Abstract
We report the first enzyme-catalysed kinetic resolution of epoxy enol esters. The lipase-promoted hydrolysis of these compounds provided α-hydroxyketones or α-hydroxyaldehydes (arising from the spontaneous rearrangement of the epoxy enols) and the residual esters with moderate to good enantioselectivity (E up to 100).
Keywords
enzyme catalysis , Hydrolases , kinetic resolution , Hydrolysis , Epoxy enol esters
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1852112
Link To Document