Title of article
Secondary systemic lupus erythematosus: An analysis of 4 cases of uncontrolled hereditary angioedema
Author/Authors
Khan، نويسنده , , Sujoy and Tarzi، نويسنده , , Michael D. and Doré، نويسنده , , Philip C. and Sewell، نويسنده , , W.A.C. and Longhurst، نويسنده , , Hilary J.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
4
From page
14
To page
17
Abstract
The association of systemic lupus erythematosus and hereditary angioedema (HAE) has formed the basis of numerous case reports and is hypothesised to result from consumption of complement C4 with consequent impaired clearance of apoptotic cells. We describe the development of frank lupus or lupus-like syndrome in four HAE patients with uncontrolled angioedema and low levels of serum C4. Measures that limit hypocomplementaemia in HAE may reduce the incidence of secondary SLE.
Keywords
systemic lupus erythematosus , Hereditary angioedema , Acquired angioedema , AAE , Complement deficiency , apoptosis , HAE
Journal title
Clinical Immunology
Serial Year
2007
Journal title
Clinical Immunology
Record number
1852195
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