Title of article
Efficient access to chiral N-substituted saccharin analogues via the directed ortho-lithiation of 3-N-arylsulfonyloxazolidin-2-ones
Author/Authors
Aliyenne، نويسنده , , A. Ould and Khiari، نويسنده , , J.E. and Kraïem، نويسنده , , J. and Kacem، نويسنده , , Y. and Hassine، نويسنده , , B. Ben، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
4
From page
6405
To page
6408
Abstract
Chiral 3-N-arylsulfonyloxazolidin-2-ones 1a–f, prepared from (l)-amino acids, were reacted with lithium diisopropylamide in anhydrous THF and HMPA. The resulting new, optically active benzisothiazolinone 1,1-dioxides 2a–c and naphthisothiazolinone 1,1-dioxides 2d–f were obtained in good yields.
Keywords
Benzisothiazolinone 1 , 1-dioxides , oxazolidinones , Directed ortho-lithiation
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1852251
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