Title of article :
An efficient solid-phase synthesis of biologically important DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepine dimers (DSB-120) and their C2-fluorinated analogues
Author/Authors :
Kamal، نويسنده , , Ahmed and Shankaraiah، نويسنده , , N. and Devaiah، نويسنده , , V. and Reddy، نويسنده , , K. Laxma، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Abstract :
A facile method for the solid-phase synthesis of pyrrolo[2,1-c][1,4]benzodiazepine dimers has been developed. p-Nitrophenyl carbonate Wang resin attached to 2-amino-5-methoxy-methyl benzoate has been utilized as the resin-bound starting material and these reactions are monitored by FT-IR spectroscopy of resin beads.
Keywords :
DSB-120 , Swern oxidation , solid-phase synthesis , 4]benzodiazepine dimers
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
