Title of article :
Pd-catalyzed asymmetric allylic alkylation with nitromethane using a chiral diaminophosphine oxide: (S,RP)-Ph-DIAPHOX. Enantioselective synthesis of (R)-preclamol and (R)-baclofen
Author/Authors :
Nemoto، نويسنده , , Tetsuhiro and Jin، نويسنده , , Long and Nakamura، نويسنده , , Hiroshi and Hamada، نويسنده , , Yasumasa، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Abstract :
A Pd-catalyzed asymmetric allylic alkylation with nitromethane using an aspartic acid-derived P-chirogenic diaminophosphine oxide [(S,RP)-Ph-DIAPHOX] is described. This method was successfully applied to enantioselective synthesis of (R)-preclamol and (R)-baclofen.
Keywords :
Catalysis , Asymmetric allylic amination , Diaminophosphine oxide , Nitromethane , PALLADIUM
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
