Title of article :
The unique regioselectivity in the formation of disubstituted-1,4-benzoquinones generated from the reaction of 4-hydroxycoumarins with 1,4-benzoquinone
Author/Authors :
Zhang، نويسنده , , Sheng-Ling and Huang، نويسنده , , Zhi-Shu and Shen، نويسنده , , Yu-Dong and Li، نويسنده , , Yue-Ming and Yao، نويسنده , , Jun-Hua and Huang، نويسنده , , Min and Chan، نويسنده , , Albert S.C. and Gu، نويسنده , , Lian-Quan، نويسنده ,
Abstract :
The 2,3-disubstituted 1,4-benzoquinones were synthesized through the regioselective addition of 4-hydroxycoumarins with 1,4-benzoquinone in aqueous acetone, which were different from 2,5-disubstituted adducts generated by the previously reported reaction of compounds possessing an activated methylene with 1,4-benzoquinone.
Keywords :
4-Hydroxycoumarins , 4-benzoquinone , Michael addition , 1
