Title of article
Solid-phase synthesis of 4-biaryl-piperidine-4-carboxamides
Author/Authors
Zhu، نويسنده , , Jin and Pottorf، نويسنده , , Richard S. and Player، نويسنده , , Mark R.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
4
From page
7267
To page
7270
Abstract
A novel solid-phase synthesis of 4-biaryl-piperidine-4-carboxamides has been developed using FDMP resin with a carboxamide as the anchor point. With this approach, three points of diversity were incorporated into a GPCR-directed scaffold. Final products were obtained in good purity and yield.
Keywords
solid-phase , Suzuki coupling , Biaryl-piperidine
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1852723
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