• Title of article

    Solid-phase synthesis of 4-biaryl-piperidine-4-carboxamides

  • Author/Authors

    Zhu، نويسنده , , Jin and Pottorf، نويسنده , , Richard S. and Player، نويسنده , , Mark R.، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2006
  • Pages
    4
  • From page
    7267
  • To page
    7270
  • Abstract
    A novel solid-phase synthesis of 4-biaryl-piperidine-4-carboxamides has been developed using FDMP resin with a carboxamide as the anchor point. With this approach, three points of diversity were incorporated into a GPCR-directed scaffold. Final products were obtained in good purity and yield.
  • Keywords
    solid-phase , Suzuki coupling , Biaryl-piperidine
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2006
  • Journal title
    Tetrahedron Letters
  • Record number

    1852723