Title of article :
Ti(NMe2)4-catalyzed Markovnikov hydroamination of alkynes in the presence of N-heterocyclic carbenes and LiN(SiMe3)2
Author/Authors :
Takaki، نويسنده , , Ken and Koizumi، نويسنده , , Sadayuki and Yamamoto، نويسنده , , Yuta and Komeyama، نويسنده , , Kimihiro، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Abstract :
Intermolecular hydroamination of alkynes catalyzed by Ti(NMe2)4 was much improved with N-heterocyclic carbenes and LiN(SiMe3)2, by which high Markovnikov selectivity was attained for the coupling of nearly all alkynes and amines.
Keywords :
N-Heterocyclic carbenes , Hydroamination , Alkynes , Lithium silylamides , Titanium catalysts
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
