Title of article :
Synthesis of hexopyranosyl acetates and 2,3-disubstituted tetrahydropyrans via chemoselective hydrogenation of hex-2-enopyranosyl acetates
Author/Authors :
Sasaki، نويسنده , , Kaname and Wakamatsu، نويسنده , , Takayuki and Matsumura، نويسنده , , Shuichi and Toshima، نويسنده , , Kazunobu، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2006
Abstract :
A simple and easy method for chemoselective synthesis of hexopyranosyl acetates and 2,3-disubstituted tetrahydropyrans from hex-2-enopyranosyl acetates was demonstrated. The former was achieved by hydrogenation catalyzed by Rh/Al2O3 in EtOAc/toluene solvent at 0 °C, while the latter was carried out using Pd/C in EtOH/AcOH at 25 °C.
Keywords :
carbohydrates , Hydrogenolysis , tetrahydropyrans , Hydrogenation , Chemoselectivity
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
