Title of article
Chemoenzymatic synthesis of enantiomerically enriched kavalactones
Author/Authors
Kamal، نويسنده , , Ahmed and Krishnaji، نويسنده , , Tadiparthi and Khanna، نويسنده , , G.B. Ramesh Khanna، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
4
From page
8657
To page
8660
Abstract
Lipase-mediated kinetic resolution of methyl-3-hydroxy-5-phenylpentanoate and (6E)-ethyl 5-hydroxy-3-oxo-7-phenylhept-6-enoate is described in high enantiomeric excess and good yields. The effect of different lipases in different solvents has been screened using different acylating agents. This protocol has been extended for the preparation of enantiomerically pure biologically important kavalactones.
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1853444
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