Author/Authors :
Mizuno، نويسنده , , Mamoru and Matsumoto، نويسنده , , Hiroharu and Goto، نويسنده , , Kohtaro and Hamasaki، نويسنده , , Keita، نويسنده ,
Abstract :
Four aminoglycoside derivatives containing a 2,6-diamino-2,6-dideoxy-d-glucopyranose disaccharide structure were successfully prepared by using a Cbz-type heavy fluorous tag in a fluorous synthesis. A Cbz-type heavy fluorous tag was prepared using the hexakis(fluorous chain)-type alcohol 11, and the fluorous alcohol 11 was recovered in good yield after the synthesis of aminoglycoside derivatives.