Title of article
1,1-Dihydroperoxycyclododecane as a new, crystalline non-hygroscopic oxidizer for the chemical synthesis of oligodeoxyribonucleotides
Author/Authors
Saneyoshi، نويسنده , , Hisao and Miyata، نويسنده , , Kenichi and Seio، نويسنده , , Kohji and Sekine، نويسنده , , Mitsuo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
3
From page
8945
To page
8947
Abstract
A new oxidation method for DNA synthesis was developed by the use of 1,1-dihydroperoxycyclododecane in CH2Cl2–EtOAc under anhydrous conditions. This new oxidizer was successfully applied to the synthesis of oligodeoxyribonucleotides that involves an oxidation step for conversion of phosphite intermediates to phosphate derivatives.
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1853589
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