Author/Authors :
Yiming and Aldeco-Pérez، نويسنده , , Eugenia and Rudler، نويسنده , , Henri and Parlier، نويسنده , , Andrée and Alvarez، نويسنده , , Cecilio and Apan، نويسنده , , Maria Teresa and Herson، نويسنده , , Patrick and Toscano، نويسنده , , Alfredo، نويسنده ,
Abstract :
A series of dihydrobenzofuran-2-one 3 have been submitted to various dienophiles: whereas maleic anhydride led only to the adducts 4a,b, singlet oxygen gave the expected new endoperoxide lactones 5a–d, 6 and 7a,b, three of them showing interesting cytotoxicity towards various cancer cell lines.
Keywords :
Endoperoxides , Lactones , cytotoxicity , Cycloadditions