Title of article
Selective Michael additions of primary and secondary amines to perfluoroalkylated sulfoxides and sulfones as a tool for fluorous tagging
Author/Authors
Caroline Magnier-Bouvier، نويسنده , , Caroline and Blazejewski، نويسنده , , Jean-Claude and Larpent، نويسنده , , Chantal and Magnier، نويسنده , , Emmanuel، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
4
From page
9121
To page
9124
Abstract
Vinyl tridecafluorohexyl sulfoxide 1 and sulfone 2 are shown to be highly reactive towards Michael addition with a broad range of secondary and primary amines. Full selectivity for monofunctionalization of primary amines can be achieved by a proper choice of reagent 1 or 2 depending on amine basicity.
Keywords
Aza-Michael , Perfluoroalkyl chains , Sulfoxide , Sulfone , Fluorous tags
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1853673
Link To Document