Title of article
Synthesis of retro-inverso peptides employing isocyanates of Nα-Fmoc-amino acids/peptide acids catalyzed by DMAP
Author/Authors
Venkataramanarao G. Anand، نويسنده , , Rao and Sureshbabu، نويسنده , , Vommina V.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
3
From page
9139
To page
9141
Abstract
The Goldschmidt–Wick type reaction between isocyanates of Nα-Fmoc-amino acids/peptide acids and Nα-Boc-/Z-/Bsmoc-amino acids catalyzed by DMAP leads to the incorporation of a reversed peptide bond. It was found to be a simple, efficient and clean reaction. All the retro-inverso peptides made were obtained as crystalline compounds in 70–92% yields.
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1853686
Link To Document