Author/Authors :
Chinni Mahesh، نويسنده , , K. and Narasimhulu، نويسنده , , M. and Srikanth Reddy، نويسنده , , T. and Suryakiran، نويسنده , , N. and Venkateswarlu، نويسنده , , Y.، نويسنده ,
Abstract :
A facile and versatile method for the chemoselective N-benzyloxycarbonylation of amines has been developed by treatment with benzyloxycarbonyl chloride (Cbz–Cl) in the presence of lanthanum(III) nitrate hexahydrate under solvent-free conditions. The method is general for the preparation of N-Cbz derivatives of aliphatic (acyclic and cyclic) and aromatic amines.
Keywords :
solvent-free conditions , La(NO3)3·6H2O , N-Benzyloxycarbonylation , Amines
