Title of article :
A formal total synthesis of crocacin C
Author/Authors :
Yadav، نويسنده , , J.S. and Reddy، نويسنده , , P. Venkatram and Chandraiah، نويسنده , , L.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2007
Abstract :
An efficient total synthesis of a potent antifungal and moderate cytotoxic agent crocacin C is described. The synthesis involves the generation of four contiguous stereogenic centres via desymmetrization of a meso bicyclic dihydrofuran using asymmetric hydroboration.
Keywords :
crocacin , cross-metathesis , Modified Julia olefination , desymmetrization
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters