Author/Authors :
Gridnev، نويسنده , , Ilya D. and Kouchi، نويسنده , , Mitsuhiro and Sorimachi، نويسنده , , Keiichi and Terada، نويسنده , , Masahiro، نويسنده ,
Abstract :
Associates between the chiral phosphoric acids and Boc-protected imine were characterized computationally and by NMR; the primary importance of the bulky protecting group in imine for the high enantioselectivity in the direct Mannich reaction is rationalized via the analysis of the stereodiscriminating intermediates.
