• Title of article

    On the mechanism of stereoselection in direct Mannich reaction catalyzed by BINOL-derived phosphoric acids

  • Author/Authors

    Gridnev، نويسنده , , Ilya D. and Kouchi، نويسنده , , Mitsuhiro and Sorimachi، نويسنده , , Keiichi and Terada، نويسنده , , Masahiro، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2007
  • Pages
    4
  • From page
    497
  • To page
    500
  • Abstract
    Associates between the chiral phosphoric acids and Boc-protected imine were characterized computationally and by NMR; the primary importance of the bulky protecting group in imine for the high enantioselectivity in the direct Mannich reaction is rationalized via the analysis of the stereodiscriminating intermediates.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2007
  • Journal title
    Tetrahedron Letters
  • Record number

    1853980