Title of article :
On the viability of 5-endo-dig cyclisations of O-propargylic hydroxylamine derivatives, leading to 2,5-dihydroisoxazoles (3-isoxazolines)
Author/Authors :
Foot، نويسنده , , Oliver F. and Knight، نويسنده , , David W. and Low، نويسنده , , Ai Cheng Lilian and Li، نويسنده , , Yingfa Li، نويسنده ,
Abstract :
O-Propargylic hydroxylamines undergo smooth 5-endo-dig cyclisations upon exposure to 3 equiv of molecular iodine to give respectable yields of the corresponding 4-iodo-2,5-dihydroisoxazoles, which should find a number of applications as intermediates for syntheses amongst this useful class of heterocycles.
