Author/Authors :
Uemura، نويسنده , , Toshiyuki and Suzuki، نويسنده , , Toshio and Onodera، نويسنده , , Naohiro and Hagiwara، نويسنده , , Hisahiro and Hoshi، نويسنده , , Takashi، نويسنده ,
Abstract :
The stereoselective total synthesis of (+)-obtusenyne is described. The oxonene skeleton possessing trans-orientated alkyl substituents at the α,α′-positions was stereoselectively constructed via cyclization of the corresponding hydroxy epoxide promoted by Eu(fod)3.
Keywords :
oxonenes , medium-ring heterocycles , cyclization , (+)-Obtusenyne , hydroxy epoxides
