Title of article
First total synthesis of topopyrone C
Author/Authors
Gattinoni، نويسنده , , Sonia and Merlini، نويسنده , , Lucio and Dallavalle، نويسنده , , Sabrina، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
3
From page
1049
To page
1051
Abstract
The first synthesis of topopyrone C, a natural compound and inhibitor of Topoisomerase I, has been carried out by Marschalk alkylation of 1-hydroxy-3,6,8-trimethoxyanthraquinone, followed by a Baker–Venkataraman chain elongation and an acid-catalyzed cyclization for the construction of the pyrone ring.
Keywords
Marschalk reaction , topoisomerase , anthraquinone , Topopyrone C , Synthesis
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1854158
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