Enantioselective Friedel–Crafts alkylation of indoles with nitroalkenes catalyzed by a bis(oxazoline)–Cu(II) complex
Author/Authors :
Singh، نويسنده , , Pradeep K. and Bisai، نويسنده , , Alakesh and Singh، نويسنده , , Vinod K.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2007
Pages :
3
From page :
1127
To page :
1129
Abstract :
The catalytic enantioselective Friedel–Crafts reaction of indole with trans-β-nitrostyrene is reported in the presence of copper triflate–bisoxazoline complexes. The reaction furnished nitroalkylated indoles in excellent yields (up to 95%) and high enantioselectivities up to an 86% ee.
