Author/Authors :
Mori، نويسنده , , Tomonori and Higashibayashi، نويسنده , , Shuhei and Goto، نويسنده , , Taiji and Kohno، نويسنده , , Mitsunori and Satouchi، نويسنده , , Yukiko and Shinko، نويسنده , , Kazuyuki and Suzuki، نويسنده , , Kengo and Suzuki، نويسنده , , Shunya and Tohmiya، نويسنده , , Hiraku and Hashimoto، نويسنده , , Kimiko and Nakata، نويسنده , , Masaya، نويسنده ,
Abstract :
We have succeeded in the total synthesis of siomycin A, a representative compound of the thiostrepton family of peptide antibiotics, featuring the one-pot cyclization–elongation of our strategic intermediates and the late-stage formations of the thiazoline and dehydroamino acid moieties.
Keywords :
Siomycin A , dehydroamino acid , Thiazoline , One-pot cyclization–elongation
