Title of article :
A highly regio- and chemoselective addition of carbon nucleophiles to pyrimidinones. A new route to C4 elaborated Biginelli compounds
Author/Authors :
Singh، نويسنده , , Kamaljit and Arora، نويسنده , , Divya and Singh، نويسنده , , Sukhdeep، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2007
Abstract :
Ethyl 6-methyl-pyrimidine-2-one-5-carboxylates react with C-nucleophiles in a diversity oriented synthetic sequence to afford C4 substituted congeners of medicinally potent Biginelli dihydropyrimidinones, in a highly regioselective manner.
Keywords :
lithiation , Carbon nucleophiles , Regioselective addition , Biginelli compounds
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
