Title of article :
Conformational analysis and selective hydrolysis of 2,5-disubstituted-1,3-dioxane-2-carboxylic acid esters
Author/Authors :
Harabe، نويسنده , , Tetsuji and Matsumoto، نويسنده , , Takatoshi and Shioiri، نويسنده , , Takayuki، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2007
Abstract :
5-Alkyl-2-methyl-2-carbomethoxy-1,3-dioxanes were found to have a cis preferential configuration in the equilibrium state, and the ester hydrolysis rate of the trans-isomers was faster than that of the cis-isomers. Conformational analysis and charge calculation of the carbomethoxy group in both dioxanes elucidated this selectivity.
Keywords :
1 , 3-Dioxane derivative , conformational analysis , selective hydrolysis , Charge calculation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
