Title of article :
gem-Difluoropropargylation of aldehydes using cat. In/Zn in aqueous media
Author/Authors :
Arimitsu، نويسنده , , Satoru and Jacobsen، نويسنده , , Jesse M. and Hammond، نويسنده , , Gerald B.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2007
Abstract :
Zn (0.9 equiv) in combination with catalytic amounts of In (0.1 equiv) and I2 (0.1 equiv) was found to effect the reaction of several difluoropropargyl bromide derivatives with aldehydes to produce gem-difluorohomopropargyl alcohols in aqueous media under conditions suitable for large scale applications.
Keywords :
Zinc , aqueous media , gem-Difluorohomopropargyl alcohols , Cat. indium
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters