Title of article
Highly stereoselective bioreduction and one-way isomerization of 2-alkyl-4,4,4-trichloro-2-butenals
Author/Authors
Li، نويسنده , , Ning and Zhang، نويسنده , , Fanglin and Gong، نويسنده , , Yuefa، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
4
From page
1895
To page
1898
Abstract
This article describes a highly stereoselective bioreduction of 2-alkyl-4,4,4-trichloro-2-butenals (1a: Me, 1b: Et) mediated by baker’s yeast (Saccharomyces cerevisiae). The E-isomers were regiospecifically converted into the saturated alcohols 2 with high enantioselectivity, whereas the Z-isomers generated in situ by a competitive one-way isomerization were reduced only into the corresponding allyl alcohols 3 during the reactions.
Keywords
Bioreduction , Baker’s yeast , 4 , One-way isomerization , 4-Trichloro-2-butenal , 4
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1854441
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