• Title of article

    A one-pot synthesis of 3-substituted-5-carbonylmethyl-1,2,4-oxadiazoles from β-keto esters and amidoximes under solvent-free conditions

  • Author/Authors

    Du، نويسنده , , Wu and Truong، نويسنده , , Quang and Qi، نويسنده , , Hongbo and Guo، نويسنده , , Yan and Chobanian، نويسنده , , Harry R. and Hagmann، نويسنده , , William K. and Hale، نويسنده , , Jeffrey J.، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2007
  • Pages
    5
  • From page
    2231
  • To page
    2235
  • Abstract
    Herein we report a high yielding one-pot ‘green’ synthesis of 3-substituted-5-carbonylmethyl-1,2,4-oxadiazoles from readily available β-keto esters and amidoximes under simple and convenient solvent-free conditions. No additional base is needed. The reaction likely goes through an acyl ketene intermediate.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2007
  • Journal title
    Tetrahedron Letters
  • Record number

    1854561