Title of article :
A concise asymmetric synthesis of (+)-muscarine from (S)-γ-hydroxymethyl-γ-butyrolactone
Author/Authors :
Boukouvalas، نويسنده , , John and Radu، نويسنده , , Ioan-Iosif and Poirier، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2007
Abstract :
A highly stereoselective synthesis of (+)-muscarine iodide has been achieved in eight steps and 20% overall yield from commercially available (S)-γ-hydroxymethyl-γ-butyrolactone.
Keywords :
2 , 3-dihydrofurans , Hydroboration , Lactones , lithiation , (+)-Muscarine , stereoselectivity
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
