Highly efficient Suzuki–Miyaura coupling reactions catalyzed by bis(oxazolinyl)phenyl–Pd(II) complex

Bis(oxazolinyl)phenyl–palladium(II)(Phebox–Pd) complexes were found to be efficient catalysts for Suzuki–Miyaura coupling reactions of aryl boronic acids and their derivatives with aryl halides to give the corresponding biaryl products in high yield along with moderate enantioslectivities in the case of axially chiral induction. The catalytic activity was attained more than 900,000 of TON and 45,000 of TOF. The catalyst can be recovered quantitatively and could be reused for Suzuki–Miyaura reactions.